Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43.
An acylation/deacylation cycle is necessary to maintain the steady-state subcellular distribution and biological activity of S-acylated peripheral proteins.Despite the progress that has been made in identifying and characterizing palmitoyltransferases (PATs), much less is known about the thioesterases involved in protein deacylation.In this work, w